Oleanane- and ursane- type triterpenoids from Eugenia grandis

Manoharan Karuppiah Pillai; David James Young

doi:10.46537/scibru.v18i1.91

Manoharan Karuppiah Pillai Faculty of Science and Technology, Department of Chemistry and Chemical Technology, National University of Lesotho, Roma Campus, P. O. Roma 180, Kingdom of Lesotho, Southern Africa
David James Young College of Engineering, Information Technology and Environment, Charles Darwin University, Darwin, NT 0909, Australia

DOI: https://doi.org/10.46537/scibru.v18i1.91

Abstract

Arjunolic acid (an oleanane-type triterpenoid) and asiatic acid (an ursane-type triterpenoid) were obtained as an inseparable mixture from a chloroform extract of stem-bark of Eugenia grandis (Myrtaceae). They were characterised mainly by analysis of their spectral data. Arjunolic acid and asiatic acid are reported to have a variety of biological and pharmacological activities, which include antibacterial, anti-inflammatory, antioxidant, antidiabetic, antihyperlipidemic, cardiacprotective, antitumor, anticancer and hepatoprotective activities. Arjunolic acid has been used as a cardio-protective phytotonic in traditional Ayurvedic medicine for centuries.